Thanks to the support from 26 participating centres around North West England and Wales, as well as generous funding from the Bowel Disease Research Foundation, the Rectal Cancer Complete Response Registry resulted in the successful collection of data for over 170 patients with a clinical complete response and the resulting Lancet Oncology publication. This has greatly improved our understanding of the oncological outcomes of patients with rectal cancer who have a clinical complete response to (chemo)-radiotherapy.
Towards the end of 2017, the decision was made to convert the OnCoRe Registry into a Research Database registered with the Health Research Authority (HRA) & with Section 251 approval from the Confidentiality Advisory Group (CAG). This will allow us to continue to add patients and follow up data to further investigate the oncological outcomes of these patients.
In December 2017, we received full REC approval and CAG Section 251 Support, with the research database approved and funded until November 2021. In May 2018, the project was accepted onto the NIHR Clinical Research Network Portfolio (CPMS ID 37613), with support available for all centres recruiting patients for inclusion into the database.
The OnCoRe Research Database is now up and running and ready to accept new patients. This website contains all the information required to submit patient data to the registry, but please get in touch if you have any questions or if there is anything we can help with.
A huge thank you to everyone who has submitted data and supported the Research Database to date – we now have data for 189 patients with a Clinical Complete Response!